Repetition priming influences distinct brain systems: evidence from task-evoked data and resting-state correlations.

ABSTRACT: Behavioral dissociations suggest that a single experience can separately influence multiple processing components. Here we used a repetition priming functional magnetic resonance imaging paradigm that directly contrasted the effects of stimulus and decision changes to identify the underlying brain systems. Direct repetition of stimulus features caused marked reductions in posterior regions of the inferior temporal lobe that were insensitive to whether the decision was held constant or changed between study and test. By contrast, prefrontal cortex showed repetition effects that were sensitive to the exact stimulus-to-decision mapping. Analysis of resting-state functional connectivity revealed that the dissociated repetition effects are embedded within distinct brain systems. Regions that we

SUBMITTER: Wig GS 

PROVIDER: S-EPMC2681438 | biostudies-literature | 2009 May

REPOSITORIES: biostudies-literature