The effect of blastomere biopsy on preimplantation mouse embryo development and global gene expression.

ABSTRACT: The blastomere biopsy procedure does not affect preimplantation embryo development or global patterns of gene expression in a mouse model of Preimplantation Genetic Testing (PGT). However, zona breaching, which is inherent to the blastomere biopsy procedure, causes significant premature and sometimes abnormal hatching.

SUBMITTER: Duncan FE 

PROVIDER: S-EPMC2683241 | biostudies-literature | 2009 Apr

REPOSITORIES: biostudies-literature