Who will participate in acute stroke trials?

ABSTRACT:

Background

Despite the high incidence of acute stroke, only a minority of patients are enrolled in acute stroke treatment trials. We aimed to identify factors associated with participation in clinical trials of novel therapeutic agents for acute stroke.

Methods

Prospective survey of patients with acute stroke <72 hours from onset. A structured interview was administered to the patient or primary decision-maker. If offered participation in an actual acute treatment trial, questions focused on decisions about that trial; otherwise a similar mock trial was proposed. The primary outcome was whether the subject agreed to participate in the proposed trial.

Results

A total of 200 subjects (47% patients, 53% proxies) completed the survey: mean age 63 +/- 14 years, 47% women,

SUBMITTER: Kasner SE 

PROVIDER: S-EPMC2683644 | biostudies-literature | 2009 May

REPOSITORIES: biostudies-literature