Caenorhabditis elegans genomic response to soil bacteria predicts environment-specific genetic effects on life history traits.

ABSTRACT: With the post-genomic era came a dramatic increase in high-throughput technologies, of which transcriptional profiling by microarrays was one of the most popular. One application of this technology is to identify genes that are differentially expressed in response to different environmental conditions. These experiments are constructed under the assumption that the differentially expressed genes are functionally important in the environment where they are induced. However, whether differential expression is predictive of functional importance has yet to be tested. Here we have addressed this expectation by employing Caenorhabditis elegans as a model for the interaction of native soil nematode taxa and soil bacteria. Using transcriptional profiling, we identified candidate genes regulated i

SUBMITTER: Coolon JD 

PROVIDER: S-EPMC2684633 | biostudies-literature | 2009 Jun

REPOSITORIES: biostudies-literature