VirHostNet: a knowledge base for the management and the analysis of proteome-wide virus-host interaction networks.

ABSTRACT: Infectious diseases caused by viral agents kill millions of people every year. The improvement of prevention and treatment of viral infections and their associated diseases remains one of the main public health challenges. Towards this goal, deciphering virus-host molecular interactions opens new perspectives to understand the biology of infection and for the design of new antiviral strategies. Indeed, modelling of an infection network between viral and cellular proteins will provide a conceptual and analytic framework to efficiently formulate new biological hypothesis at the proteome scale and to rationalize drug discovery. Therefore, we present the first release of VirHostNet (Virus-Host Network), a public knowledge base specialized in the management and analysis of integrated virus-viru

SUBMITTER: Navratil V 

PROVIDER: S-EPMC2686459 | biostudies-literature | 2009 Jan

REPOSITORIES: biostudies-literature