Identification of genes expressed in the hermaphrodite germ line of C. elegans using SAGE.

ABSTRACT:

Background

Germ cells must progress through elaborate developmental stages from an undifferentiated germ cell to a fully differentiated gamete. Some of these stages include exiting mitosis and entering meiosis, progressing through the various stages of meiotic prophase, adopting either a male (sperm) or female (oocyte) fate, and completing meiosis. Additionally, many of the factors needed to drive embryogenesis are synthesized in the germ line. To increase our understanding of the genes that might be necessary for the formation and function of the germ line, we have constructed a SAGE library from hand dissected C. elegans hermaphrodite gonads.

Results

We found that 4699 genes, roughly 21% of all known C. elegans genes, are expressed in the adult hermaphrodite germ line. Rib

SUBMITTER: Wang X 

PROVIDER: S-EPMC2686737 | biostudies-literature | 2009 May

REPOSITORIES: biostudies-literature