Phenotypic diversity of infectious red sea bream iridovirus isolates from cultured fish in Japan.

ABSTRACT: Megalocytivirus is causing economically serious mass mortality by infecting fish in and around the Pacific region of Asia. The recent emergence of many new iridoviruses has drawn attention to the marked taxonomic variation within this virus family. Most studies of these viruses have not included extensive study of these emergent species. We explored the emergence of red sea bream iridovirus (RSIV) on a fish farm in Japan, and we specifically endeavored to quantify genetic and phenotypic differences between RSIV isolates using in vitro and in vivo methods. The three isolates had identical major capsid protein sequences, and they were closely related to Korean RSIV isolates. In vitro studies revealed that the isolates differed in replication rate, which was determined by real-time quantitati

SUBMITTER: Shinmoto H 

PROVIDER: S-EPMC2687316 | biostudies-literature | 2009 Jun

REPOSITORIES: biostudies-literature