Haplotype structure strongly affects recombination in a maize genetic interval polymorphic for Helitron and retrotransposon insertions.

ABSTRACT: We have asked here how the remarkable variation in maize haplotype structure affects recombination. We compared recombination across a genetic interval of 9S in 2 highly dissimilar heterozygotes that shared 1 parent. The genetic interval in the common haplotype is approximately 100 kb long and contains 6 genes interspersed with gene-fragment-bearing Helitrons and retrotransposons that, together, comprise 70% of its length. In one heterozygote, most intergenic insertions are homozygous, although polymorphic, enabling us to determine whether any recombination junctions fall within them. In the other, most intergenic insertions are hemizygous and, thus, incapable of homologous recombination. Our analysis of the frequency and distribution of recombination in the interval revealed that: (i) Mos

SUBMITTER: He L 

PROVIDER: S-EPMC2688972 | biostudies-literature | 2009 May

REPOSITORIES: biostudies-literature