Impact of intraoperative lung-protective interventions in patients undergoing lung cancer surgery.

ABSTRACT:

Introduction

In lung cancer surgery, large tidal volume and elevated inspiratory pressure are known risk factors of acute lung (ALI). Mechanical ventilation with low tidal volume has been shown to attenuate lung injuries in critically ill patients. In the current study, we assessed the impact of a protective lung ventilation (PLV) protocol in patients undergoing lung cancer resection.

Methods

We performed a secondary analysis of an observational cohort. Demographic, surgical, clinical and outcome data were prospectively collected over a 10-year period. The PLV protocol consisted of small tidal volume, limiting maximal pressure ventilation and adding end-expiratory positive pressure along with recruitment maneuvers. Multivariate analysis with logistic regression was performed

SUBMITTER: Licker M 

PROVIDER: S-EPMC2689485 | biostudies-literature | 2009

REPOSITORIES: biostudies-literature