MitoMiner, an integrated database for the storage and analysis of mitochondrial proteomics data.

ABSTRACT: Mitochondria are a vital component of eukaryotic cells with functions that extend beyond energy production to include metabolism, signaling, cell growth, and apoptosis. Their dysfunction is implicated in a large number of metabolic, degenerative, and age-related human diseases. Therefore, it is important to characterize and understand the mitochondrion. Many experiments have attempted to define the mitochondrial proteome, resulting in large and complex data sets that are difficult to analyze. To address this, we developed a new public resource for the storage and investigation of this mitochondrial proteomics data, called MitoMiner, that uses a model to describe the proteomics data and associated biological information. The proteomics data of 33 publications from both mass spectrometry and

SUBMITTER: Smith AC 

PROVIDER: S-EPMC2690483 | biostudies-literature | 2009 Jun

REPOSITORIES: biostudies-literature