Systematic review of hydroxychloroquine use in pregnant patients with autoimmune diseases.

ABSTRACT:

Objective

The purpose of this study is to compare the incidence of congenital defects, spontaneous abortions, number of live births, fetal death and pre-maturity in women with autoimmune diseases taking HCQ during pregnancy.

Methods

The authors searched MEDLINE, Cochrane data base, Ovid-Currents Clinical Medicine, Ovid-Embase:Drugs and Pharmacology, EBSCO, Web of Science, and SCOPUS using the search terms HCQ and/or pregnancy. We attempted to identify all clinical trials from 1980 to 2007 regardless of language or publication status. We also searched Cochrane Central Library and http://www.Clinical trials.gov for clinical trials of HCQ and pregnancy. Data were extracted onto standardized forms and were confirmed.

Results

The odds ratio (OR) of congenital defects in li

SUBMITTER: Sperber K 

PROVIDER: S-EPMC2690583 | biostudies-literature | 2009 May

REPOSITORIES: biostudies-literature