Prospective study of sleep-disordered breathing and hypertension: the Sleep Heart Health Study.

ABSTRACT:

Rationale

Cross-sectional epidemiologic studies show an association between sleep-disordered breathing and hypertension, but only one cohort study has examined sleep-disordered breathing as a risk factor for incident hypertension.

Objectives

To examine whether sleep-disordered breathing increases the risk of incident hypertension among persons 40 years of age and older.

Methods

In a prospective cohort study, we analyzed data from 2,470 participants who at baseline did not have hypertension, defined as blood pressure of at least 140/90 mm Hg or taking antihypertensive medication. The apnea-hypopnea index (AHI), the number of apneas plus hypopneas per hour of sleep, was measured by overnight in-home polysomnography. We estimated odds ratios for developing hypertension d

SUBMITTER: O'Connor GT 

PROVIDER: S-EPMC2695498 | biostudies-literature | 2009 Jun

REPOSITORIES: biostudies-literature