Comparative analysis of embryonic cell lineage between Caenorhabditis briggsae and Caenorhabditis elegans.

ABSTRACT: Comparative genomic analysis of important signaling pathways in Caenorhabditis briggsae and Caenorhabditis elegans reveals both conserved features and also differences. To build a framework to address the significance of these features we determined the C. briggsae embryonic cell lineage, using the tools StarryNite and AceTree. We traced both cell divisions and cell positions for all cells through all but the last round of cell division and for selected cells through the final round. We found the lineage to be remarkably similar to that of C. elegans. Not only did the founder cells give rise to similar numbers of progeny, the relative cell division timing and positions were largely maintained. These lineage similarities appear to give rise to similar cell fates as judged both by the positi

SUBMITTER: Zhao Z 

PROVIDER: S-EPMC2696483 | biostudies-literature | 2008 Feb

REPOSITORIES: biostudies-literature