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The genomics of speciation in Drosophila: diversity, divergence, and introgression estimated using low-coverage genome sequencing.


ABSTRACT: In nature, closely related species may hybridize while still retaining their distinctive identities. Chromosomal regions that experience reduced recombination in hybrids, such as within inversions, have been hypothesized to contribute to the maintenance of species integrity. Here, we examine genomic sequences from closely related fruit fly taxa of the Drosophila pseudoobscura subgroup to reconstruct their evolutionary histories and past patterns of genic exchange. Partial genomic assemblies were generated from two subspecies of Drosophila pseudoobscura (D. ps.) and an outgroup species, D. miranda. These new assemblies were compared to available assemblies of D. ps. pseudoobscura and D. persimilis, two species with overlapping ranges in western North America. Within inverted regions, nucleo

SUBMITTER: Kulathinal RJ 

PROVIDER: S-EPMC2696600 | biostudies-literature | 2009 Jul

REPOSITORIES: biostudies-literature