Prostate cancer-derived urine exosomes: a novel approach to biomarkers for prostate cancer.

ABSTRACT: Herein, we describe a novel approach in the search for prostate cancer biomarkers, which relies on the transcriptome within tumour exosomes. As a proof-of-concept, we show the presence of two known prostate cancer biomarkers, PCA-3 and TMPRSS2:ERG the in exosomes isolated from urine of patients, showing the potential for diagnosis and monitoring cancer patients status.

SUBMITTER: Nilsson J 

PROVIDER: S-EPMC2696767 | biostudies-literature | 2009 May

REPOSITORIES: biostudies-literature