Soy proteins and isoflavones affect bone mineral density in older women: a randomized controlled trial.

ABSTRACT:

Background

Soy foods contain several components (isoflavones and amino acids) that potentially affect bone. Few long-term, large clinical trials of soy as a means of improving bone mineral density (BMD) in late postmenopausal women have been conducted.

Objective

Our goal was to evaluate the long-term effect of dietary soy protein and/or soy isoflavone consumption on skeletal health in late postmenopausal women.

Design

We conducted a randomized, double-blind, placebo-controlled clinical trial in 131 healthy ambulatory women aged >60 y. Ninety-seven women completed the trial. After a 1-mo baseline period, subjects were randomly assigned into 1 of 4 intervention groups: soy protein (18 g) + isoflavone tablets (105 mg isoflavone aglycone equivalents), soy protein + placeb

SUBMITTER: Kenny AM 

PROVIDER: S-EPMC2697003 | biostudies-literature | 2009 Jul

REPOSITORIES: biostudies-literature