Transducin beta-like gene FTL1 is essential for pathogenesis in Fusarium graminearum.

ABSTRACT: Fusarium head blight caused by Fusarium graminearum is an important disease of wheat and barley. In a previous study, we identified several mutants with reduced virulence by insertional mutagenesis. A transducin beta-like gene named FTL1 was disrupted in one of these nonpathogenic mutants. FTL1 is homologous to Saccharomyces cerevisiae SIF2, which is a component of the Set3 complex involved in late stages of ascospore formation. The Delta ftl1 mutant was significantly reduced in conidiation and failed to cause typical disease symptoms. It failed to colonize the vascular tissues of rachis or cause necrosis on the rachis of inoculated wheat heads. The Delta ftl1 mutant also was defective in spreading from infected anthers to ovaries and more sensitive than the wild type to plant defensins Ms

SUBMITTER: Ding S 

PROVIDER: S-EPMC2698311 | biostudies-literature | 2009 Jun

REPOSITORIES: biostudies-literature