The Gene Ontology's Reference Genome Project: a unified framework for functional annotation across species.

ABSTRACT: The Gene Ontology (GO) is a collaborative effort that provides structured vocabularies for annotating the molecular function, biological role, and cellular location of gene products in a highly systematic way and in a species-neutral manner with the aim of unifying the representation of gene function across different organisms. Each contributing member of the GO Consortium independently associates GO terms to gene products from the organism(s) they are annotating. Here we introduce the Reference Genome project, which brings together those independent efforts into a unified framework based on the evolutionary relationships between genes in these different organisms. The Reference Genome project has two primary goals: to increase the depth and breadth of annotations for genes in each of the

SUBMITTER: Reference Genome Group of the Gene Ontology Consortium 

PROVIDER: S-EPMC2699109 | biostudies-literature | 2009 Jul

REPOSITORIES: biostudies-literature