LeishCyc: a biochemical pathways database for Leishmania major.

ABSTRACT:

Background

Leishmania spp. are sandfly transmitted protozoan parasites that cause a spectrum of diseases in more than 12 million people worldwide. Much research is now focusing on how these parasites adapt to the distinct nutrient environments they encounter in the digestive tract of the sandfly vector and the phagolysosome compartment of mammalian macrophages. While data mining and annotation of the genomes of three Leishmania species has provided an initial inventory of predicted metabolic components and associated pathways, resources for integrating this information into metabolic networks and incorporating data from transcript, protein, and metabolite profiling studies is currently lacking. The development of a reliable, expertly curated, and widely available model of Leishmani

SUBMITTER: Doyle MA 

PROVIDER: S-EPMC2700086 | biostudies-literature | 2009 Jun

REPOSITORIES: biostudies-literature