Simulation of the cost-effectiveness of malaria vaccines.

ABSTRACT:

Background

A wide range of possible malaria vaccines is being considered and there is a need to identify which vaccines should be prioritized for clinical development. An important element of the information needed for this prioritization is a prediction of the cost-effectiveness of potential vaccines in the transmission settings in which they are likely to be deployed. This analysis needs to consider a range of delivery modalities to ensure that clinical development plans can be aligned with the most appropriate deployment strategies.

Methods

The simulations are based on a previously published individual-based stochastic model for the natural history and epidemiology of Plasmodium falciparum malaria. Three different vaccine types: pre-erythrocytic vaccines (PEV), blood stag

SUBMITTER: Tediosi F 

PROVIDER: S-EPMC2701956 | biostudies-literature | 2009 Jun

REPOSITORIES: biostudies-literature