Improving quality of colonoscopy by adding simethicone to sodium phosphate bowel preparation.

ABSTRACT:

Aim

To evaluate the effectiveness of simethicone in enhancing visibility and efficacy during colonoscopy.

Methods

A prospective, double-blind, randomized, placebo-controlled study was conducted. One hundred and twenty-four patients were allocated to receive 2 doses of sodium phosphate plus 240 mg of tablet simethicone or placebo as bowel preparation. Visibility was blindly assessed for the amount of air bubbles and adequacy of colon preparation. Total colonoscopic time, side effects of the medication, endoscopist and patient satisfaction were also compared.

Results

Sodium phosphate plus simethicone, compared to sodium phosphate plus placebo, improved visibility by diminishing air bubbles (100.00% vs 42.37%, P < 0.0001) but simethicone failed to demonstrate improvement

SUBMITTER: Tongprasert S 

PROVIDER: S-EPMC2702112 | biostudies-literature | 2009 Jun

REPOSITORIES: biostudies-literature