LPS-induced genes in intestinal tissue of the sea cucumber Holothuria glaberrima.

ABSTRACT: Metazoan immunity is mainly associated with specialized cells that are directly involved with the immune response. Nevertheless, both in vertebrates and invertebrates other organs might respond to immune activation and participate either directly or indirectly in the ongoing immune process. However, most of what is known about invertebrate immunity has been restricted to immune effector cells and little information is available on the immune responses of other tissues or organs. We now focus on the immune reactions of the intestinal tissue of an echinoderm. Our study employs a non-conventional model, the echinoderm Holothuria glaberrima, to identify intestinal molecules expressed after an immune challenge presented by an intra-coelomic injection of lipopolysaccharides (LPS). The expression

SUBMITTER: Ramirez-Gomez F 

PROVIDER: S-EPMC2702171 | biostudies-literature | 2009 Jul

REPOSITORIES: biostudies-literature