Development of an integrative database with 499 novel microsatellite markers for Macaca fascicularis.

ABSTRACT:

Background

Cynomolgus macaques (Macaca fascicularis) are a valuable resource for linkage studies of genetic disorders, but their microsatellite markers are not sufficient. In genetic studies, a prerequisite for mapping genes is development of a genome-wide set of microsatellite markers in target organisms. A whole genome sequence and its annotation also facilitate identification of markers for causative mutations. The aim of this study is to establish hundreds of microsatellite markers and to develop an integrative cynomolgus macaque genome database with a variety of datasets including marker and gene information that will be useful for further genetic analyses in this species.

Results

We investigated the level of polymorphisms in cynomolgus monkeys for 671 microsatellite ma

SUBMITTER: Higashino A 

PROVIDER: S-EPMC2702342 | biostudies-literature | 2009 Jun

REPOSITORIES: biostudies-literature