SeeMotif: exploring and visualizing sequence motifs in 3D structures.

ABSTRACT: Sequence motifs are important in the study of molecular biology. Motif discovery tools efficiently deliver many function related signatures of proteins and largely facilitate sequence annotation. As increasing numbers of motifs are detected experimentally or predicted computationally, characterizing the functional roles of motifs and identifying the potential synergetic relationships between them are important next steps. A good way to investigate novel motifs is to utilize the abundant 3D structures that have also been accumulated at an astounding rate in recent years. This article reports the development of the web service seeMotif, which provides users with an interactive interface for visualizing sequence motifs on protein structures from the Protein Data Bank (PDB). Researchers can qu

SUBMITTER: Chang DT 

PROVIDER: S-EPMC2703912 | biostudies-literature | 2009 Jul

REPOSITORIES: biostudies-literature