First detection of plasmid-encoded blaOXY beta-lactamase.

ABSTRACT: Three Klebsiella oxytoca isolates and one Klebsiella pneumoniae isolate from three children admitted to the Hematology Unit of Hospital Vall d'Hebron (Barcelona, Spain) exhibited a susceptibility pattern suggesting OXY beta-lactamase hyperproduction. All the isolates contained a 95-kb plasmid that harbored bla(OXY-1), which was transferred by electrotransformation but could not be self-transferred by conjugation. A qnrS1 gene was also harbored in the bla(OXY-1)-carrying plasmid. This is the first report of a plasmid-encoded OXY beta-lactamase.

SUBMITTER: Gonzalez-Lopez JJ 

PROVIDER: S-EPMC2704681 | biostudies-literature | 2009 Jul

REPOSITORIES: biostudies-literature