Comprehensive esophageal microscopy by using optical frequency-domain imaging (with video).

ABSTRACT:

Background

Optical coherence tomography (OCT) has been used for high-resolution endoscopic imaging and diagnosis of specialized intestinal metaplasia, dysplasia, and intramucosal carcinoma of the esophagus. However, the relatively slow image-acquisition rate of the present OCT systems inhibits wide-field imaging and limits the clinical utility of OCT for diagnostic imaging in patients with Barrett's esophagus.

Objective

This study describes a new optical imaging technology, optical frequency-domain imaging (OFDI), derived from OCT, that enables comprehensive imaging of large esophageal segments with microscopic resolution.

Design

A prototype OFDI system was developed for endoscopic imaging. The system was used in combination with a balloon-centering catheter to compre

SUBMITTER: Vakoc BJ 

PROVIDER: S-EPMC2705339 | biostudies-literature | 2007 May

REPOSITORIES: biostudies-literature