Effects of flexible-dose fesoterodine on overactive bladder symptoms and treatment satisfaction: an open-label study.

ABSTRACT:

Aims

To evaluate the efficacy and tolerability of flexible-dose fesoterodine in subjects with overactive bladder (OAB) who were dissatisfied with previous tolterodine treatment.

Methods

This was a 12-week, open-label, flexible-dose study of adults with OAB (> or = 8 micturitions and > or = 3 urgency episodes per 24 h) who had been treated with tolterodine (immediate- or extended-release) for OAB within 2 years of screening and reported dissatisfaction with tolterodine treatment. Subjects received fesoterodine 4 mg once daily for 4 weeks; thereafter, daily dosage was maintained at 4 mg or increased to 8 mg based on the subject's and physician's subjective assessment of efficacy and tolerability. Subjects completed 5-day diaries, the Patient Perception of Bladder Condition (PP

SUBMITTER: Wyndaele JJ 

PROVIDER: S-EPMC2705818 | biostudies-literature | 2009 Apr

REPOSITORIES: biostudies-literature