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Atosiban versus betamimetics in the treatment of preterm labour in Germany: an economic evaluation.


ABSTRACT:

Background

The use of tocolytics is central in delaying birth; however, therapeutic options vary in effectiveness and adverse events profiles, which in turn could have consequences for medical resource use and cost of treatment. Betamimetics are commonly used tocolytic agents, but their mechanism of action affects multiple organ systems leading to numerous adverse events. The availability of an oxytocin receptor antagonist, specific for prevention of preterm labour, offers a treatment option that merits further evaluation. We aimed to compare economic implications of tocolysis using atosiban and betamimetics, considering treatment efficacy and safety, as well as cost consequences of treatment of associated adverse events.

Methods

A systematic literature review identified six

SUBMITTER: Wex J 

PROVIDER: S-EPMC2708127 | biostudies-literature | 2009 Jun

REPOSITORIES: biostudies-literature