LD2SNPing: linkage disequilibrium plotter and RFLP enzyme mining for tag SNPs.

ABSTRACT:

Background

Linkage disequilibrium (LD) mapping is commonly used to evaluate markers for genome-wide association studies. Most types of LD software focus strictly on LD analysis and visualization, but lack supporting services for genotyping.

Results

We developed a freeware called LD2SNPing, which provides a complete package of mining tools for genotyping and LD analysis environments. The software provides SNP ID- and gene-centric online retrievals for SNP information and tag SNP selection from dbSNP/NCBI and HapMap, respectively. Restriction fragment length polymorphism (RFLP) enzyme information for SNP genotype is available to all SNP IDs and tag SNPs. Single and multiple SNP inputs are possible in order to perform LD analysis by online retrieval from HapMap and NCBI. An LD

SUBMITTER: Chang HW 

PROVIDER: S-EPMC2709117 | biostudies-literature | 2009 Jun

REPOSITORIES: biostudies-literature