HAPPI: an online database of comprehensive human annotated and predicted protein interactions.

ABSTRACT:

Background

Human protein-protein interaction (PPIs) data are the foundation for understanding molecular signalling networks and the functional roles of biomolecules. Several human PPI databases have become available; however, comparisons of these datasets have suggested limited data coverage and poor data quality. Ongoing collection and integration of human PPIs from different sources, both experimentally and computationally, can enable disease-specific network biology modelling in translational bioinformatics studies.

Results

We developed a new web-based resource, the Human Annotated and Predicted Protein Interaction (HAPPI) database, located at http://bio.informatics.iupui.edu/HAPPI/. The HAPPI database was created by extracting and integrating publicly available protein i

SUBMITTER: Chen JY 

PROVIDER: S-EPMC2709259 | biostudies-literature | 2009 Jul

REPOSITORIES: biostudies-literature