Comparative genomics and evolution of conserved noncoding elements (CNE) in rainbow trout.

ABSTRACT:

Background

Recent advances in the accumulation of genetic mapping and DNA sequence information from several salmonid species support the long standing view of an autopolyploid origin of these fishes (i.e., 4R). However, the paralogy relationships of the chromosomal segments descendent from earlier polyploidization events (i.e., 2R/3R) largely remain unknown, mainly due to an unbalanced pseudogenization of paralogous genes that were once resident on the ancient duplicated segments. Inter-specific conserved noncoding elements (CNE) might hold the key in identifying these regions, if they are associated with arrays of genes that have been highly conserved in syntenic blocks through evolution. To test this hypothesis, we investigated the chromosomal positions of subset of CNE in the ra

SUBMITTER: Moghadam HK 

PROVIDER: S-EPMC2711117 | biostudies-literature | 2009 Jun

REPOSITORIES: biostudies-literature