Pharmacological plus optical penalization treatment for amblyopia: results of a randomized trial.

ABSTRACT:

Objective

To compare weekend atropine sulfate use augmented by a plano lens for the sound eye with weekend atropine use alone for moderate amblyopia in children aged 3 years to younger than 7 years.

Methods

In a multicenter clinical trial, 180 children with moderate amblyopia (visual acuities of 20/40-20/100) were randomized to weekend atropine use augmented by a plano lens or weekend atropine use alone.

Main outcome measure

Masked assessment of amblyopic eye visual acuity using the Amblyopia Treatment Study HOTV testing protocol at 18 weeks.

Results

At 18 weeks, amblyopic eye improvement averaged 2.8 lines in the group that received atropine plus a plano lens and 2.4 lines in the group that received atropine alone (mean difference between groups adjusted for b

SUBMITTER: Pediatric Eye Disease Investigator Group 

PROVIDER: S-EPMC2713107 | biostudies-literature | 2009 Jan

REPOSITORIES: biostudies-literature