A comprehensive resource for integrating and displaying protein post-translational modifications.

ABSTRACT:

Background

Protein Post-Translational Modification (PTM) plays an essential role in cellular control mechanisms that adjust protein physical and chemical properties, folding, conformation, stability and activity, thus also altering protein function.

Findings

dbPTM (version 1.0), which was developed previously, aimed on a comprehensive collection of protein post-translational modifications. In this update version (dbPTM2.0), we developed a PTM database towards an expert system of protein post-translational modifications. The database comprehensively collects experimental and predictive protein PTM sites. In addition, dbPTM2.0 was extended to a knowledge base comprising the modified sites, solvent accessibility of substrate, protein secondary and tertiary structures, protein d

SUBMITTER: Lee TY 

PROVIDER: S-EPMC2713254 | biostudies-literature | 2009 Jun

REPOSITORIES: biostudies-literature