Correlation of flicker-induced and flow-mediated vasodilatation in patients with endothelial dysfunction and healthy volunteers.

ABSTRACT: OBJECTIVE Flicker-induced vasodilatation is reduced in patients with vascular-related diseases, which has at least partially been attributed to endothelial dysfunction of retinal vessels. Currently, the standard method to assess endothelial function in vivo is flow-mediated vasodilatation (FMD). Thus, the present study was performed to investigate whether a correlation exists between flicker-induced vasodilatation and FMD in patients with known endothelial dysfunction and healthy subjects. RESEARCH DESIGN AND METHODS In the present study, 20 patients with type 1 diabetes, 40 patients with systemic hypertension (systolic blood pressure 140-159 mmHg; diastolic blood pressure 90-99 mmHg) and/or serum cholesterol levels > or =0.65 mmol/l, and 20 healthy control subjects were included. The flic

SUBMITTER: Pemp B 

PROVIDER: S-EPMC2713642 | biostudies-literature | 2009 Aug

REPOSITORIES: biostudies-literature