Depression precipitated by alcohol use in patients with co-occurring bipolar and substance use disorders.

ABSTRACT:

Objective

Bipolar disorder and substance use disorder frequently co-occur. However, little is known about the near-term effects of substance use on bipolar disorder. Thus, the present study tests whether alcohol use precipitates depression among patients with co-occurring bipolar disorder and substance use disorder.

Method

This study uses data collected as part of 2 clinical trials (the first study was conducted from March 1999 through March 2004 and the second study was conducted from August 2003 through May 2007) of a manualized group therapy for patients with co-occurring bipolar disorder and substance dependence. One hundred fifteen participants were assessed at baseline and each month through month 8. Baseline diagnoses were made using the Structured Clinical Interview

SUBMITTER: Jaffee WB 

PROVIDER: S-EPMC2713748 | biostudies-literature | 2009 Feb

REPOSITORIES: biostudies-literature