Five-year follow-up optic disc findings of the Collaborative Initial Glaucoma Treatment Study.

ABSTRACT:

Purpose

To determine the effect of intraocular pressure (IOP) lowering on the optic disc in patients of the Collaborative Initial Glaucoma Treatment Study (CIGTS) after 5 years.

Design

Randomized clinical trial.

Methods

The baseline and 5-year stereoscopic optic disc photographs of 348 eyes (patients) randomized to medical or surgical treatment of open-angle glaucoma (OAG) were assessed by 2 independent readers for change in a masked side-by-side comparison, and confirmed by an independent committee.

Results

Three hundred and three (87.1%) eyes showed no change, 22 (6.3%) showed enlargement of the cup along any meridian (progression), and 23 (6.6%) showed a reduction in the cup along any meridian (reversal of cupping). Incidence of optic disc progression was hi

SUBMITTER: Parrish RK 

PROVIDER: S-EPMC2714658 | biostudies-literature | 2009 Apr

REPOSITORIES: biostudies-literature