Intraoperative ultrasound-guided iodine-125 seed implantation for unresectable pancreatic carcinoma.

ABSTRACT:

Background

To assess the feasibility and efficacy of using 125I seed implantation under intraoperative ultrasound guidance for unresectable pancreatic carcinoma.

Methods

Fourteen patients with pancreatic carcinoma that underwent laparotomy and considered unresectable were included in this study. Nine patients were pathologically diagnosed with Stage II disease, five patients with Stage III disease. Fourteen patients were treated with 125I seed implantation guided by intraoperative ultrasound and received D90 of 125I seeds ranging from 60 to 140 Gy with a median of 120 Gy. Five patients received an additional 35-50 Gy from external beam radiotherapy after seed implantation and six patients received 2-6 cycles of chemotherapy.

Results

87.5% (7/8) of patients received pa

SUBMITTER: Wang J 

PROVIDER: S-EPMC2715376 | biostudies-literature | 2009 Jun

REPOSITORIES: biostudies-literature