Insertion of horizontally transferred genes within conserved syntenic regions of yeast genomes.

ABSTRACT: Horizontal gene transfer has been occasionally mentioned in eukaryotic genomes, but such events appear much less numerous than in prokaryotes, where they play important functional and evolutionary roles. In yeasts, few independent cases have been described, some of which corresponding to major metabolic functions, but no systematic screening of horizontally transferred genes has been attempted so far. Taking advantage of the synteny conservation among five newly sequenced and annotated genomes of Saccharomycetaceae, we carried out a systematic search for HGT candidates amidst genes present in only one species within conserved synteny blocks. Out of 255 species-specific genes, we discovered 11 candidates for HGT, based on their similarity with bacterial proteins and on reconstructed phyloge

SUBMITTER: Rolland T 

PROVIDER: S-EPMC2715888 | biostudies-literature | 2009 Aug

REPOSITORIES: biostudies-literature