PairWise Neighbours database: overlaps and spacers among prokaryote genomes.

ABSTRACT:

Background

Although prokaryotes live in a variety of habitats and possess different metabolic and genomic complexity, they have several genomic architectural features in common. The overlapping genes are a common feature of the prokaryote genomes. The overlapping lengths tend to be short because as the overlaps become longer they have more risk of deleterious mutations. The spacers between genes tend to be short too because of the tendency to reduce the non coding DNA among prokaryotes. However they must be long enough to maintain essential regulatory signals such as the Shine-Dalgarno (SD) sequence, which is responsible of an efficient translation.

Description

PairWise Neighbours is an interactive and intuitive database used for retrieving information about the spacers and

SUBMITTER: Palleja A 

PROVIDER: S-EPMC2716372 | biostudies-literature | 2009 Jun

REPOSITORIES: biostudies-literature