Epidemiology of breast cancer subtypes in two prospective cohort studies of breast cancer survivors.

ABSTRACT:

Introduction

The aim of this study was to describe breast tumor subtypes by common breast cancer risk factors and to determine correlates of subtypes using baseline data from two pooled prospective breast cancer studies within a large health maintenance organization.

Methods

Tumor data on 2544 invasive breast cancer cases subtyped by estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 (Her2) status were obtained (1868 luminal A tumors, 294 luminal B tumors, 288 triple-negative tumors and 94 Her2-overexpressing tumors). Demographic, reproductive and lifestyle information was collected either in person or by mailed questionnaires. Case-only odds ratios (ORs) and 95% confidence intervals (CIs) were estimated using logistic regression, adjustin

SUBMITTER: Kwan ML 

PROVIDER: S-EPMC2716499 | biostudies-literature | 2009

REPOSITORIES: biostudies-literature