OVEX1, a novel chicken endogenous retrovirus with sex-specific and left-right asymmetrical expression in gonads.

ABSTRACT:

Background

In chickens, as in most birds, female gonad morphogenesis is asymmetrical. Gonads appear first rather similarly, but only the left one undergoes full differentiation and gives rise to a functional ovary. The right gonad, in which the cortex does not develop, remains restricted to the medulla and finally regresses. Opportunity was taken of this left-right asymmetry to perform a suppression subtractive hybridization screening to select for transcripts preferentially expressed in the developing left ovary as compared to the right one, and thus identify genes that are potentially involved in the process of ovarian differentiation.

Results

One of these transcripts, named Ovex1 according to its expression profile, corresponds to an endogenous retrovirus that has not bee

SUBMITTER: Carre-Eusebe D 

PROVIDER: S-EPMC2717909 | biostudies-literature | 2009 Jun

REPOSITORIES: biostudies-literature