Outcome of asthma and wheezing in the first 6 years of life: follow-up through adolescence.

ABSTRACT:

Rationale

The effect of early life wheezing on respiratory function and continued symptoms through adolescence has not been fully described. Using data from a population-based birth cohort in Tucson, Arizona, we previously described four phenotypes based on the occurrence of wheezing lower respiratory illnesses before age 3 yr and active wheeze at age 6 yr: never wheezers (n = 425), transient early wheezers (n = 164), persistent wheezers (n = 113), and late-onset wheezers (n = 124).

Objective

We sought to determine the prognosis for these phenotypes, with reference to lung function and symptoms, through adolescence.

Methods

Current wheeze was assessed by questionnaire, lung function was measured by conventional spirometry, and atopy was determined by skin prick tests.

SUBMITTER: Morgan WJ 

PROVIDER: S-EPMC2718414 | biostudies-literature | 2005 Nov

REPOSITORIES: biostudies-literature