Using neuroplasticity-based auditory training to improve verbal memory in schizophrenia.

ABSTRACT:

Objective

Impaired verbal memory in schizophrenia is a key rate-limiting factor for functional outcome, does not respond to currently available medications, and shows only modest improvement after conventional behavioral remediation. The authors investigated an innovative approach to the remediation of verbal memory in schizophrenia, based on principles derived from the basic neuroscience of learning-induced neuroplasticity. The authors report interim findings in this ongoing study.

Method

Fifty-five clinically stable schizophrenia subjects were randomly assigned to either 50 hours of computerized auditory training or a control condition using computer games. Those receiving auditory training engaged in daily computerized exercises that placed implicit, increasing demands on

SUBMITTER: Fisher M 

PROVIDER: S-EPMC2720319 | biostudies-literature | 2009 Jul

REPOSITORIES: biostudies-literature