Zebrafish RNase T2 genes and the evolution of secretory ribonucleases in animals.

ABSTRACT:

Background

Members of the Ribonuclease (RNase) T2 family are common models for enzymological studies, and their evolution has been well characterized in plants. This family of acidic RNases is widespread, with members in almost all organisms including plants, animals, fungi, bacteria and even some viruses. While several biological functions have been proposed for these enzymes in plants, their role in animals is unknown. Interestingly, in vertebrates most of the biological roles of plant RNase T2 proteins are carried out by members of a different family, RNase A. Still, RNase T2 proteins are conserved in these animals

Results

As a first step to shed light on the role of animal RNase T2 enzymes, and to understand the evolution of these proteins while co-existing with the RNas

SUBMITTER: Hillwig MS 

PROVIDER: S-EPMC2720953 | biostudies-literature | 2009 Jul

REPOSITORIES: biostudies-literature