Genetic diversity and population structure of Plasmodium falciparum in Thailand, a low transmission country.

ABSTRACT:

Background

The population structure of the causative agents of human malaria, Plasmodium sp., including the most serious agent Plasmodium falciparum, depends on the local epidemiological and demographic situations, such as the incidence of infected people, the vector transmission intensity and migration of inhabitants (i.e. exchange between sites). Analysing the structure of P. falciparum populations at a large scale, such as continents, or with markers that are subject to non-neutral selection, can lead to a masking and misunderstanding of the effective process of transmission. Thus, knowledge of the genetic structure and organization of P. falciparum populations in a particular area with neutral genetic markers is needed to understand which epidemiological factors should be targe

SUBMITTER: Pumpaibool T 

PROVIDER: S-EPMC2722663 | biostudies-literature | 2009 Jul

REPOSITORIES: biostudies-literature