Mapping anatomical connectivity patterns of human cerebral cortex using in vivo diffusion tensor imaging tractography.

ABSTRACT: The characterization of the topological architecture of complex networks underlying the structural and functional organization of the brain is a basic challenge in neuroscience. However, direct evidence for anatomical connectivity networks in the human brain remains scarce. Here, we utilized diffusion tensor imaging deterministic tractography to construct a macroscale anatomical network capturing the underlying common connectivity pattern of human cerebral cortex in a large sample of subjects (80 young adults) and further quantitatively analyzed its topological properties with graph theoretical approaches. The cerebral cortex was divided into 78 cortical regions, each representing a network node, and 2 cortical regions were considered connected if the probability of fiber connections excee

SUBMITTER: Gong G 

PROVIDER: S-EPMC2722790 | biostudies-literature | 2009 Mar

REPOSITORIES: biostudies-literature