Efficacy and safety of aripiprazole in the treatment of bipolar disorder: a systematic review.

ABSTRACT:

Background

The current article is a systematic review concerning the efficacy and safety of aripiprazole in the treatment of bipolar disorder.

Methods

A systematic Medline and repositories search concerning the usefulness of aripiprazole in bipolar disorder was performed, with the combination of the words 'aripiprazole' and 'bipolar'.

Results

The search returned 184 articles and was last updated on 15 April 2009. An additional search included repositories of clinical trials and previous systematic reviews specifically in order to trace unpublished trials. There were seven placebo-controlled randomised controlled trials (RCTs), six with comparator studies and one with add-on studies. They assessed the usefulness of aripiprazole in acute mania, acute bipolar depression

SUBMITTER: Fountoulakis KN 

PROVIDER: S-EPMC2724509 | biostudies-literature | 2009 Jul

REPOSITORIES: biostudies-literature