Human papillomavirus genotype specificity of hybrid capture 2 low-risk probe cocktail.

ABSTRACT: A genotyping study of 285 Hybrid Capture 2 low-risk probe cocktail-positive specimens showed cross-reactivity with several untargeted human papillomavirus genotypes. Cross-reactivity was often clinically beneficial due to the detection of untargeted low-risk genotypes. A total of 8.4% of positive results, usually weak, were due to cross-reactivity with high-risk genotypes. Establishment of a gray zone is recommended.

SUBMITTER: Poljak M 

PROVIDER: S-EPMC2725686 | biostudies-literature | 2009 Aug

REPOSITORIES: biostudies-literature