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Genetic stasis of dominant West Nile virus genotype, Houston, Texas.


ABSTRACT: The accumulation and fixation of mutations in West Nile virus (WNV) led to the emergence of a dominant genotype throughout North America. Subsequent analysis of 44 isolates, including 19 new sequences, from Houston, Texas, suggests that WNV has reached relative genetic stasis at the local level in recent years.

SUBMITTER: Davis CT 

PROVIDER: S-EPMC2725985 | biostudies-literature | 2007 Apr

REPOSITORIES: biostudies-literature

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Genetic stasis of dominant West Nile virus genotype, Houston, Texas.

Davis C Todd CT   Li Li L   May Fiona J FJ   Bueno Rudy R   Dennett James A JA   Bala Adil A AA   Guzman Hilda H   Quiroga-Elizondo Darwin D   Tesh Robert B RB   Barrett Alan D AD  

Emerging infectious diseases 20070401 4


The accumulation and fixation of mutations in West Nile virus (WNV) led to the emergence of a dominant genotype throughout North America. Subsequent analysis of 44 isolates, including 19 new sequences, from Houston, Texas, suggests that WNV has reached relative genetic stasis at the local level in recent years. ...[more]

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