Anti-fibrinolytic agents in post partum haemorrhage: a systematic review.

ABSTRACT:

Background

Post partum haemorrhage is a leading cause of maternal death worldwide. It also contributes to maternal morbidity as women may require a hysterectomy to control bleeding, or may require a blood transfusion, which can transmit viral infections. Anti-fibrinolytic agents have been proposed as a treatment for post partum haemorrhage. We conducted a systematic review to assess the effectiveness and safety of anti-fibrinolytic agents in post partum bleeding.

Methods

All randomised controlled trials of anti-fibrinolytic agents given for bleeding during the postpartum period were included in this review. We searched Medline, PubMed, EMBASE, Cochrane Central Register of Controlled trials, Web of Science, metaRegister of controlled trials, LILACS, Reproductive Health Librar

SUBMITTER: Ferrer P 

PROVIDER: S-EPMC2727491 | biostudies-literature | 2009 Jul

REPOSITORIES: biostudies-literature